Diagnosing CIRS can be complex. It often involves a combination of a detailed medical history, symptom evaluation, visual contrast sensitivity (VCS) testing, laboratory testing (such as biomarker analysis), and potentially other specialized assessments like genetic testing or imaging studies. Working with a healthcare professional experienced in CIRS diagnosis is crucial. Here is a brief explanation of some of the diagnostic tests that may be used:

VCS Screening:
VCS tests the contrast function of vision, or the ability to see an edge. This test looks at the graded change of contrast at different light frequency used to make a grid of five separate frequencies. The test can be used to determine a biotoxin illness such as CIRS.

NeuroQuant is a volume measurement on 11 paired brain structures based on one sagittal view MRI without contrast. Using tables based on thousands of patient studies it can differentiate type of exposure based on brain injury pattern. NeuroQuant testing often can detect the exposure that cased the patient’s CIRS. This test can be used for both diagnosing CIRS and evaluation of the effectiveness of treatment.

Genie is a gene expression test preformed on a single blood specimen. This test examines the activity of 188+ genes. It examines the activity of these genes that have the most important impact on the diagnosis and treatment of CIRS patients.